226 Skin controls gut immune function through innate immune ECM cross talk
نویسندگان
چکیده
منابع مشابه
Sliver nanoparticles accelerate skin wound healing in mice (Mus musculus) through suppression of innate immune system
Objective(s): This study aimed to find the effects of silver nanoparticles (Ag-NPs) (40 nm) on skin wound healing in mice Mus musculus when innate immune system has been suppressed.Materials and Methods: A group of 50 BALB/c mice of about 8 weeks (weighting 24.2±3.0 g) were randomly divided into two groups: Ag-NPs and control group, each with 25 mice. Once a day at the same time, a volume of 50...
متن کاملsliver nanoparticles accelerate skin wound healing in mice (mus musculus) through suppression of innate immune system
objective(s): this study aimed to find the effects of silver nanoparticles (ag-nps) (40 nm) on skin wound healing in mice mus musculus when innate immune system has been suppressed.materials and methods: a group of 50 balb/c mice of about 8 weeks (weighting 24.2±3.0 g) were randomly divided into two groups: ag-nps and control group, each with 25 mice. once a day at the same time, a volume of 50...
متن کاملNovel cross-talk within the IKK family controls innate immunity.
Members of the IKK {IκB [inhibitor of NF-κB (nuclear factor κB)] kinase} family play a central role in innate immunity by inducing NF-κB- and IRF [IFN (interferon) regulatory factor]-dependent gene transcription programmes required for the production of pro-inflammatory cytokines and IFNs. However, the molecular mechanisms that activate these protein kinases and their complement of physiologica...
متن کاملNeonatal programming of innate immune function.
The early life environment can be crucial in influencing the development of an animal's long-term physiology. There is now much evidence to suggest that perinatal challenges to an animal's immune system will result in changes in adult rat behavior, physiology, and molecular pathways following a single inflammatory event during development caused by the bacterial endotoxin lipopolysaccharide (LP...
متن کاملInnate Immune Function of Mitochondrial Metabolism
Sensing of microbe-associated molecular patterns or danger signals by innate immune receptors drives a complex exchange of information. Innate receptor signaling not only triggers transcriptional events but also induces profound changes in metabolic fluxes, redox balance, and metabolite abundance thereby influencing immune cell function. Mitochondria are at the core of metabolic adaptation to t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2020
ISSN: 0022-202X
DOI: 10.1016/j.jid.2020.03.231